十三水群
PerkinElmer

小動物活體成像

IVIS Lumina S5 and Lumina X5 2D optical imaging systems
IVIS Lumina S5 and Lumina X5 2D optical imaging systems

NEW IVIS Lumina S5 & X5

  • High-sensitivity 2D optical imaging (bioluminescence and fluorescence)
  • High resolution, low dose X-ray with optical overlay (IVIS Lumina X5 only)
  • High-throughput format with a 20 x 20 FOV sufficient for imaging 5 mice simultaneously
  • Compact design that fits on your benchtop
  • Unique animal handling accessories and software tools to streamline throughput
IVIS Lumina III Series 2D optical imaging systems
IVIS Lumina III Series 2D optical imaging systems

IVIS Lumina III Series

  • 2D optical imaging (bioluminescence and fluorescence)
  • Low-dose X-ray with optical overlay (IVIS Lumina XRMS only)
  • Images up to 3 mice simultaneously
  • Compact design that fits on your benchtop
IVIS Spectrum Series 2D & 3D optical imaging systems
IVIS Spectrum Series 2D & 3D optical imaging systems

IVIS Spectrum Series

  • 2D optical imaging (bioluminescence and fluorescence)
  • 3D optical tomography for bioluminescence & fluorescence imaging
  • Low-dose ultra-fast integrated microCT (IVIS SpectrumCT only)
  • Images 5 mice simultaneously with ability to expand to 10 mice with upgrade (IVIS Spectrum & IVIS SpectrumCT only)
  • Images 10 mice simultaneously (IVIS SpectrumBL only)
產品與服務 (12)
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顯像模式
  • Optical Imaging (10)
  • microCT Imaging (2)
  • PET Imaging (1)
長度
  • 51-100 (8)
  • 41-50 (3)
  • 901-1000 (1)
產品品牌名稱
  • IVIS (7)
  • FMT (3)
  • Quantum (1)
  • G-Platform (1)

1-12 的 12 產品與服務

  • FMT In Vivo Imaging Instrument

    FMT 1000 In Vivo Imaging System

    The FMT? 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
  • IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

    IVIS Lumina XRMS 小動物活體成像系統

    IVIS? Lumina XRMS III是PerkinElmer最新推出的二維多模式活體成像系統,具備最高靈敏度的生物發光、多光譜熒光、放射性同位素和X光活體成像功能。
  • FMT In Vivo Imaging Instrument

    FMT 4000 In Vivo Imaging System

    The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
  • IVIS Lumina S5 high throughput, high sensitivity optical in vivo imaging system

    IVIS Lumina S5成像系統

    IVIS Lumina S5是PerkinElmer最新推出的第四代小動物活體光學二維成像平臺。該系統秉承了前幾代IVIS系列共有的作為業內金標準的高靈敏度生物發光成像性能,以及專利的熒光多光譜掃描及分離(Spectral unmixing)成像性能。
  • Quantum GX2 microCT imaging system

    Quantum GX2 microCT成像系統

    應用領域涉及骨、腫瘤、心血管和肺部等疾病研究。Quantum GX2 micro CT成像系統模式靈活,兼容離體樣本、小鼠、大鼠及兔子等多種物種;具備快速、低劑量的掃描模式,適合對活體動物進行長時程研究;具備高分辨率成像特點,能夠對離體樣本進行高分辨掃描。 Quantum GX2 microCT卓越的性能讓您不僅得到圖像,而是更深入的理解疾病模型。
  • IVIS Spectrum In Vivo Imaging System

    IVIS Spectrum 小動物活體成像系統

    IVIS? Spectrum 小動物活體光學成像系統是全球首臺同時具備生物發光、熒光、化學發光及切倫科夫二維/三維成像功能的系統,代表了目前活體光學成像技術的最高水平。
  • G8 PET/CT benchtop scanner for preclinical imaging research

    G8 PET/CT 成像系統集

    PerkinElmer 公司最新研發的 G8 PET/CT 二合一成像系統集成了高靈敏度 PET 成像及快速、低劑量 microCT 成像,使研究者在進行功能或代謝研究的同時,獲取結構性圖像數據。
  • IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

    IVIS SpectrumCT 小動物活體成像系統

    IVIS? Spectrum CT是全球頂尖的小動物活體三維光學/CT二合一成像系統。
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS Lumina III 小動物活體成像系統

    IVIS? Lumina III是PerkinElmer最新推出的第三代高靈敏度多光譜小動物活體光學二維成像平臺。
  • IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

    IVIS Lumina LT 小動物活體成像系統

    IVIS? Lumina LT是PerkinElmer最新推出的第三代高靈敏度小動物活體光學二維成像平臺。
  • IVIS Lumina X5 in vivo imaging system

    IVIS Lumina X5成像系統

    PerkinElmer全新一代小動物活體成像系統IVIS Lumina X5整合了最佳的高通量生物發光、熒光及高分辨率二維X光成像模塊。擴展為五只小鼠的光學及X光大成像視野、獨特的實驗設置和樣品標記輔助配件讓研究人員能更便捷、更快速地獲取疾病進展中解剖學和功能學各方面的穩定數據和答案。
  • FMT In Vivo Imaging Instrument

    FMT 2000 In Vivo Imaging System

    The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
Business Insights (11)
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資源庫
  • Application Note (8)
  • Poster (3)

1-11 的 11 Business Insights

  • 應用文獻

    Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000

    Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing tumor progression or response to therapy. This approach for tumor assessment requires the use of near infrared (NIR) imaging agents specific for different aspects of tumor biology, and this Application Note highlights the ease and utility of multiplex NIR fluorescence imaging to characterize the complex biology within tumors growing in a living mouse.

  • 應用文獻

    Contrast-enhanced Imaging of Vasculature and Soft Tissues Using the Quantum GX MicroCT System

    X-ray CT imaging is commonly used for skeletal imaging as bones are densely mineralized tissues with excellent x-ray attenuation properties. In contrast, soft, less dense tissues often prove to be challenging to image due to their lack of sufficient tissue density. Soft tissues such as muscle, blood vessels and internal organs share similar x-ray attenuation characteristics and are not distinguishable under typical CT settings. In order to introduce density that would improve soft tissue contrast, several contrast agents have been developed for use in clinical and preclinical settings. This application note outlines the use of iodine and nanoparticle-based contrast agents for imaging soft tissues and vasculature in various organs using the Quantum GX to gain further insights into disease and therapeutic response.

  • 應用文獻

    Stem Cell Research and Regenerative Medicine

    With the potential to treat a wide range of disease, from organ damage to congenital defects, stem cell research and tissue engineering form the underlying basis of regenerative medicine. Significant advances in the science of skin regeneration, for example, have now made it possible to develop and grow artificial skin grafts in a lab for treatment of burn victims. Other therapeutic applications include the use of stem cells to treat and repair central nervous system diseases such as ischemia and cerebral palsy, cardiovascular diseases, as well as autoimmune diseases including type I diabetes.

  • 應用文獻

    Vascular Imaging Probes For Oncology and Inflammation Using the IVIS Spectrum

    Optical-based in vivo imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. A number of fluorescent imaging probes that circulate with the blood, but have no target selectivity, have been used to detect tumor leakiness as an indication of abnormal tumor vasculature. Inflammation is also characterized by distinct vascular changes, including vasodilation and increased vascular permeability, which are induced by the actions of various inflammatory mediators. This process is essential for facilitating access for appropriate cells, cytokines, and other factors to tissue sites in need of healing or protection from infection. This application note investigates the use of three fluorescent imaging probes, to detect and monitor vascular leak and inflammation in preclinical mouse breast cancer models.

  • 應用文獻

    MicroCT Investigation of Bone Erosion and Deformation in an Osteoarthritic Rat Model

    Osteoarthritis (OA) is the most common form of arthritis and affects a considerable portion of the elderly population. In the U.S., it is estimated that more than 630 million people worldwide have this chronic condition, generally in the knees. OA occurs when the cartilage that cushions the ends of bones within the joints gradually deteriorates, causing synovitis and joint deformation.

    The goal of OA research is to identify new therapeutic strategies that could prevent, reduce, halt progression, or repair the existing damage to the joint. Non-invasive in vivo imaging such as microCT is the standard modality for bone research due to its ability to obtain high-resolution images at an x-ray dose low enough as not to harm the animal. This makes microCT ideal for monitoring disease progression and response to treatments in the same animal over time. However, microCT data visualization and analysis can be cumbersome and time consuming. In this application note, we compared standard microCT software and advanced bone software to investigate bone erosion in an OA rat model.

  • 應用文獻

    NIR Fluorescent Cell Labeling for In Vivo Cell Tracking (VivoTrack 680)

    Fluorescent dyes have been used for many years to label cells for microscopy studies, and a variety of dyes in the visible fluorescence spectrum are available to label different cellular compartments and organelles. Efficient delivery of the fluorophore to the cell without excessively modifying surface proteins or perturbing cell function is the major biotechnological challenge. In addition, researchers have taken on the challenge of in vivo imaging, focusing on near infrared (NIR) dyes that fluoresce in a spectral region better suited for in vivo imaging due to reduced background and higher tissue penetration.

  • 應用文獻

    Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V

    Drug induced liver injury (DILI) is a major reason for late stage termination of drug discovery research projects, highlighting the importance of early integration of liver safety assessment in the drug development process. A technical approach for in vivo toxicology determination was developed using Acetaminophen (APAP), a commonly used over-the-counter analgesic and antipyretic drug, to induce acute hepatocellular liver injury.

  • 應用文獻

    Preclinical Fluorescence Imaging of Cancer Metastasis to the Lung and Response to Therapy

    Quantitative pre-clinical fluorescence imaging transcends the boundaries of traditional optical imaging of biological structures and physiology by providing information at the molecular level about disease states and therapeutic response. Fluorescent Pre-clinical Imaging Agents and FMT? (Fluorescence Molecular Tomography) Quantitative Pre-clinical Imaging Systems represent powerful tools for research and drug development in the imaging of biological processes and pharmaceutical activity in living animals.

  • 海報

    In vivo fluorescent imaging of tumor bombesin and transferrin receptor expression as early indicators of sorafenib efficacy in small animal models

    Targeted cancer therapy aims to block key signaling pathways that are critical for tumor cell growth and survival. The blockage eventually results in cell death via apoptosis and eventual tumor growth suppression. This strategy has proven to be quite effective, and the FDA has approved several targeted therapeutics in the past decade. Encouraged by the success in clinical development, many academic and pharmaceutical researchers are in active pursuit of improved next generation targeted anti-cancer drugs. As a result, many new chemical and biological entities are emerging from initial screening of in vitro, in vitro and/or in silico selection processes. From the perspective of drug development, it poses a great challenge for the next stage of in vivo validation and demands a robust, accurate, and efficient method for assessment of these candidates in living animal models.

  • 海報

    Combined efficacy & toxicity imaging following acute 5-FU treatment of HT-29 tumor xenografts

    Cancer chemotherapy can produce severe side effects such as suppression of immune function and damage to heart muscle, gastrointestinal tract, and liver. If serious enough, tissue injury can be a major reason for late stage termination of drug discovery research projects, so it is becoming more important to integrate safety/toxicology assessments earlier in the drug development process. There are a variety of traditional serum markers, tailored mechanistically to specific tissues, however there are no current non-invasive assessment tools that are capable of looking broadly at in situ biological changes in target and non-target tissue induced by chemical insult.

  • 海報

    Molecular imaging of tumor energy metabolism as an early indicator of anti-cancer drug efficacy in small animal models

    Targeted cancer therapy aims to block key signaling pathways that are critical for tumor cell growth and survival. The blockage eventually results in cell death via apoptosis and tumor growth suppression. Encouraged by the success in clinical development, many academic and pharmaceutical researcher are in active pursuit of the improvement of next generation targeted anti-cancer drugs. As a result, many new chemical and biological entities are emerging from initial screening of in vitro, in vitro and/or in silico selection processes. From the perspective of drug development, it poses a great challenge on the next stage of in vivo validation and demands a robust, accurate, and efficient method for assessment of these candidates in living animal models.

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